Carlos and Miguel Bertonatti are the founders of the Medical Health Institute, one of the nation’s top optimization clinics specializing in biohacking, hormone therapy, and personalized health solutions. Their mission is to help patients look, feel, and perform at their best through customized protocols that blend ancestral wisdom with advanced medical science.

Chronic disease and accelerated aging have become major challenges in today’s world. Many people are searching for strategies to improve their vitality, build muscle health, balance hormones, and extend longevity. Carlos and Miguel’s unique approach goes beyond simply prescribing medications, focusing instead on bio-individual care.

Hormone Deficiency and Muscle Loss

Hormonal imbalances are becoming increasingly common and have a direct impact on muscle health and overall longevity. Environmental factors such as endocrine-disrupting chemicals (EDCs)—found in plastics, personal care products, and even air particulates—can disrupt hormone production and lead to deficiencies.

“Most patients we see are hormonally deficient, and that has a direct impact on muscle health and longevity,” they explain.

Low hormone levels, particularly testosterone, can slow muscle protein synthesis, resulting in muscle loss and anabolic resistance, which is the inability to efficiently build and maintain lean muscle mass. This decline can eventually lead to sarcopenia, a progressive loss of muscle that is closely linked with frailty and reduced lifespan.

Muscle Health: Building, Not Just Eating Protein

There is a common misconception that eating more protein automatically leads to more muscle. While dietary protein is important, the ability to make protein at the cellular level is what truly drives muscle growth and retention. As we age, the body becomes less efficient at balancing protein breakdown and rebuilding, a process known as proteostasis.

“Loss of proteostasis—the body’s ability to balance protein breakdown and rebuilding—is a hallmark of aging,” they explain. “We must support the body’s ability to make protein for long-term muscle health.”

MYOS MD as Part of a Longevity Protocol

One emerging tool in the effort to preserve muscle mass is MYOS MD, a nutritional supplement powered by Fortetropin®. Clinical research shows that MYOS MD can increase muscle protein synthesis and reduce muscle breakdown, even in the absence of exercise.

“In older adults, we’ve seen up to an 18% increase in muscle protein synthesis in just 21 days. That level of improvement can be transformative for individuals who struggle to maintain muscle mass.”

By supporting muscle health at the cellular level, MYOS MD can also benefit metabolic function and recovery, making it a valuable addition to longevity-focused protocols.

Hormone Optimization for Healthy Aging

Hormones play a critical role in far more than energy or sexual health. They affect cardiovascular function, bone density, cognitive clarity, immune function, and more. Restoring hormones to optimal levels can help preserve muscle mass, maintain energy balance, and slow the biological aging process.

“When hormones are balanced, we see improvements across nearly every system in the body, from muscle health to brain function,” they explain.

Modern science supports the safe and effective use of bioidentical hormones when administered correctly. Hormone optimization can serve as a foundation for long-term vitality and better healthspan.

AI and Genetics: The Future of Personalization

The next evolution of health optimization lies in the integration of artificial intelligence and genetic testing. These tools can provide an unprecedented level of personalization by mapping genetic expression, identifying deficiencies or weaknesses, and tailoring supplementation, hormone protocols, and peptides to each individual.

“AI and genetics are the future. They allow us to move away from a one-size-fits-all model and give patients the precision care they deserve,” they explain.

As AI becomes more advanced, it can streamline diagnostics, cross-reference medical data, and support more precise, individualized care. This personalized approach helps patients focus on what their unique biology needs most.

A Holistic Model for Muscle Health and Longevity

Muscle health, hormones, and longevity are deeply interconnected. Addressing hormone deficiencies, reducing exposure to endocrine-disrupting chemicals, supporting proteostasis, and leveraging advanced technologies can help slow the biological aging process.

A strong foundation of balanced hormones, proper nutrition, targeted supplementation, and lifestyle strategies can allow individuals to maintain muscle mass, enhance energy, and extend their healthspan.